I think she'll be okay eventually. It hurts, especially remembering the time she got to spend with Delta. And she views that time with a critical eye and resents it a bit. She's just out of Rapture and determined that she's going to have the life her father would have wanted her to and she's not sure that's what she did before. So onto new things? All the new things?

She won't really distance herself from her friends from before, but she'll hang around the children's home for a bit to see what normal teenagers are like, because she doesn't feel like she got that the first time around. She might just start jumping into all kinds of random things and figuring out what kind of skills she can pull from her ADAM memories (like the piano playing from her debut) and see if she can make a go out of anything there. She's going to play it very much by ear.